XXXX syndrome, a chromosomal disorder
XXXX Reserve Corps, a German military formation
XXXX (TV channel), a television channel in Italy
A shortened version of "XXXXL" or "4XL", a plus-size clothing size that generally means extra extra extra extra large
XXXX, the main character in the film Layer Cake
XXXX, symbolizing kisses at the end of written communications, similar to "XOXO" for "Hugs and kisses"
XXXX Island, a privately owned island
Castlemaine XXXX, a brand of beer
Fourecks, a continent in the fictional Discworld
