Matthew announced at the end of his show on 26 August 2006 that owing to ill-health he would be taking several weeks off his Radio 2 show, for the first time in sixteen years. Johnnie Walker was the main host in his absence.[12] Sandie Shaw, Joe Brown and Suzi Quatro were also guest hosts. Matthew returned to the show and the station on 10 February 2007.[12]
Matthew won a Sony Gold Award in 2008: "To celebrate an impressive record of more than 50 years of national and international radio broadcasting. For that lifetime career and in recognition of a truly outstanding contribution to UK radio."[10] On 29 October 2016 Matthew became the oldest regular broadcaster on BBC Radio, following Desmond Carrington's retirement.[13]
On 26 November 2016, Tim Rice stood in as presenter of the show. Rice announced that he would be sitting in for a few weeks since Matthew was "under the weather".[14] In fact, Matthew had suffered a fall at home and had spent a few weeks in hospital.